D89.81 (Graft-versus-host disease) is an umbrella ICD-10-CM medical diagnosis code in the Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism chapter. It identifies cases of graft-versus-host disease for clinical documentation, billing and epidemiological tracking.

ICD-10-CM · Category

D89.81 — Graft-versus-host disease

Chapter D50-D89: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

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Sub-codes under D89.81

D89.810Acute graft-versus-host diseaseD89.811Chronic graft-versus-host diseaseD89.812Acute on chronic graft-versus-host diseaseD89.813Graft-versus-host disease, unspecified

Related diagnoses

D89.82Autoimmune lymphoproliferative syndrome [ALPS]D89.83Cytokine release syndromeD89.84IgG4-related diseaseD89.89Oth disrd involving the immune mechanism, NEC

Common questions about D89.81 (Graft-versus-host disease)

What does ICD-10 code D89.81 mean?
D89.81 is the ICD-10-CM 2025 code for Graft-versus-host disease. ICD-10-CM is the medical coding system used by clinicians, hospitals and insurers worldwide to classify diseases and conditions in a standard way.
Is D89.81 a billable diagnosis code?
D89.81 is a category-level (umbrella) code rather than a billable specific code. For billing purposes, clinicians typically use a more specific sub-code under D89.81. Browse the sub-codes listed on this page.
Which ICD-10 chapter does D89.81 belong to?
D89.81 belongs to the chapter "Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism" (codes D50-D89). ICD-10-CM organises codes into 22 chapters by body system or condition type, which helps clinicians navigate related diagnoses.
Where can I get plain-language information about Graft-versus-host disease?
For a plain-language explanation of Graft-versus-host disease, ask GoDavaii's Health AI - it explains medical conditions in 22+ Indian languages, free, with no signup. Tap "Ask GoDavaii AI about Graft-versus-host disease" above to get a personalised answer.

Source: ICD-10-CM 2025 (Centers for Medicare & Medicaid Services, public domain). Codes valid from October 1, 2024. CMS source ↗