D57.81 (Other sickle-cell disorders with crisis) is an umbrella ICD-10-CM medical diagnosis code in the Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism chapter. It identifies cases of other sickle-cell disorders with crisis for clinical documentation, billing and epid

ICD-10-CM · Category

D57.81 — Other sickle-cell disorders with crisis

Chapter D50-D89: Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism

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Sub-codes under D57.81

D57.811Other sickle-cell disorders with acute chest syndromeD57.812Other sickle-cell disorders with splenic sequestrationD57.813Other sickle-cell disorders with cerebral vascular invlD57.814Other sickle-cell disorders with dactylitisD57.818Other sickle-cell disorders with crisis with oth compD57.819Other sickle-cell disorders with crisis, unspecified

Related diagnoses

D57.80Other sickle-cell disorders without crisis

Common questions about D57.81 (Other sickle-cell disorders with crisis)

What does ICD-10 code D57.81 mean?
D57.81 is the ICD-10-CM 2025 code for Other sickle-cell disorders with crisis. ICD-10-CM is the medical coding system used by clinicians, hospitals and insurers worldwide to classify diseases and conditions in a standard way.
Is D57.81 a billable diagnosis code?
D57.81 is a category-level (umbrella) code rather than a billable specific code. For billing purposes, clinicians typically use a more specific sub-code under D57.81. Browse the sub-codes listed on this page.
Which ICD-10 chapter does D57.81 belong to?
D57.81 belongs to the chapter "Diseases of the blood and blood-forming organs and certain disorders involving the immune mechanism" (codes D50-D89). ICD-10-CM organises codes into 22 chapters by body system or condition type, which helps clinicians navigate related diagnoses.
Where can I get plain-language information about Other sickle-cell disorders with crisis?
For a plain-language explanation of Other sickle-cell disorders with crisis, ask GoDavaii's Health AI - it explains medical conditions in 90+ languages, free, with no signup. Tap "Ask GoDavaii AI about Other sickle-cell disorders with crisis" above to get a personalised answer.

Source: ICD-10-CM 2025 (Centers for Medicare & Medicaid Services, public domain). Codes valid from October 1, 2024. CMS source ↗