Common side effects of Rofecoxib include Allergic cutaneous angiitis, Angioedema, Anxiety. Serious side effects include Agranulocytosis and Anaphylactic shock. Rofecoxib is classified as Medicine. Always consult a doctor if side effects persist.

Side Effects GuideAI-VerifiedMedicine

Rofecoxib Side Effects

Complete guide to Rofecoxib side effects — what's common, what's serious, which body systems are affected, and when to see a doctor.

Body impact map

Common
Serious
9+
Common effects
9+
Serious effects
5+
Body systems

Common Side Effects

Usually mild · often resolve on their own

These side effects may occur in some patients taking Rofecoxib. Most are mild and improve as your body adjusts. Tell your doctor if any persist or worsen.

Allergic cutaneous angiitis
Whole body
Angioedema
Skin
Anxiety
Mental / Nervous
Aplastic anaemia
Whole body
Asthma
Whole body
Bradycardia
Whole body
Bronchitis
Whole body
Bronchospasm
Whole body
Abdominal distension
Stomach / GI
Abdominal pain
Stomach / GI

Serious Side Effects

Rare but urgent · seek immediate medical help

Stop taking Rofecoxib and seek immediate medical help if any of the following occur. Call 112 for emergencies.

Emergency · 112
Agranulocytosis
Whole body
Anaphylactic shock
Whole body
Atrial fibrillation
Whole body
Basal cell carcinoma
Whole body
Breast cancer
Hormones
Cardiac failure congestive
Heart / Lungs
Deep vein thrombosis
Whole body
Duodenal perforation
Whole body
Gastric perforation
Stomach / GI
Gastrointestinal haemorrhage
Stomach / GI

Not a complete list. Report any unusual symptoms to your doctor immediately.

How to Minimize Side Effects

Simple steps that help

  • Take Rofecoxib exactly as prescribed by your doctor — never change the dose yourself.
  • Follow dosage timing instructions carefully (with food / empty stomach / at bedtime as directed).
  • Do not stop Rofecoxib suddenly without consulting your doctor — sudden discontinuation can be risky.
  • Report any new or unusual symptoms to your doctor promptly — early detection prevents complications.
  • Check drug interactions with GoDavaii AI before starting any new medicine, supplement, or even herbal remedy.
  • Avoid alcohol while on Rofecoxib unless your doctor has confirmed it is safe.
AI-Verified · Cross-checked against 40,000+ interaction database

Not medical advice

Individual responses to Rofecoxib vary — age, weight, existing conditions, and other medicines all matter. Always consult your doctor for personalized advice. For emergencies, call 112.

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