Common side effects of Donepezil include Vomiting (2344), Diarrhea (1718), Ulcer (872). Serious side effects include Seizure (576) and Bleeding (572). Donepezil is classified as Medicine. Always consult a doctor if side effects persist.

Side Effects GuideAI-VerifiedMedicine

Donepezil Side Effects

Complete guide to Donepezil side effects — what's common, what's serious, which body systems are affected, and when to see a doctor.

Body impact map

Common
Serious
9+
Common effects
9+
Serious effects
3
Body systems

Common Side Effects

Usually mild · often resolve on their own

These side effects may occur in some patients taking Donepezil. Most are mild and improve as your body adjusts. Tell your doctor if any persist or worsen.

Vomiting (2344)
Stomach / GI
Diarrhea (1718)
Stomach / GI
Ulcer (872)
Stomach / GI
Depression (654)
Mental / Nervous
Confusion (377)
Mental / Nervous
Infection (327)
Whole body
Hypertension (307)
Whole body
Duodenal ulcer (200)
Stomach / GI
Nausea (2301)
Stomach / GI
Pain (1307)
Whole body

Serious Side Effects

Rare but urgent · seek immediate medical help

Stop taking Donepezil and seek immediate medical help if any of the following occur. Call 112 for emergencies.

Emergency · 112
Seizure (576)
Mental / Nervous
Bleeding (572)
Whole body
Seizures (572)
Mental / Nervous
Hallucination (377)
Mental / Nervous
Hallucinations (327)
Mental / Nervous
Hemorrhage (327)
Whole body
Haemorrhage (150)
Whole body
Fibrillation (100)
Whole body
Perforation (100)
Whole body
Haemorrhage of digestive tract (100)
Whole body

Not a complete list. Report any unusual symptoms to your doctor immediately.

How to Minimize Side Effects

Simple steps that help

  • Take Donepezil exactly as prescribed by your doctor — never change the dose yourself.
  • Follow dosage timing instructions carefully (with food / empty stomach / at bedtime as directed).
  • Do not stop Donepezil suddenly without consulting your doctor — sudden discontinuation can be risky.
  • Report any new or unusual symptoms to your doctor promptly — early detection prevents complications.
  • Check drug interactions with GoDavaii AI before starting any new medicine, supplement, or even herbal remedy.
  • Avoid alcohol while on Donepezil unless your doctor has confirmed it is safe.
AI-Verified · Cross-checked against 40,000+ interaction database

Not medical advice

Individual responses to Donepezil vary — age, weight, existing conditions, and other medicines all matter. Always consult your doctor for personalized advice. For emergencies, call 112.

Frequently Asked Questions

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