Naproxen Sodium(275 Mg) in pregnancy: classified as Category C. Naproxen Sodium(275 Mg) pregnancy safety: Category C — Use with caution. Risk Summary Use of NSAIDs, including naproxen and esomeprazole magnesium delayed-release tablets, c

Pregnancy SafetyUse With CautionFDA Cat. CAI-Verified

Is Naproxen Sodium(275 Mg) safe during pregnancy?

Risk Summary Use of NSAIDs, including naproxen and esomeprazole magnesium delayed-release tablets, can cause premature closure of the fetal ductus arteriosus and fetal and renal dysfunction leading to oligohydramnios and, in some cases, neonatal renal impairment.

SAFECAUTIONAVOID

Overall verdict

Use With Caution

Trimester-by-Trimester Guide

40 weeks · 3 stages · different risks

AVOID
AVOID
AVOID
Week 1
Week 13
Week 27Week 40
Avoid

1st Trimester

Weeks 1–12 · Organs forming

Risk Summary Use of NSAIDs, including naproxen and esomeprazole magnesium delayed-release tablets, can cause premature closure of the fetal ductus arteriosus and fetal and renal dysfunction leading to oligohydramnios and, in some cases, neonatal renal impairment.

Avoid

2nd Trimester

Weeks 13–26 · Baby growing

Risk Summary Use of NSAIDs, including naproxen and esomeprazole magnesium delayed-release tablets, can cause premature closure of the fetal ductus arteriosus and fetal and renal dysfunction leading to oligohydramnios and, in some cases, neonatal renal impairment.

Avoid

3rd Trimester

Weeks 27–40 · Final development

Risk Summary Use of NSAIDs, including naproxen and esomeprazole magnesium delayed-release tablets, can cause premature closure of the fetal ductus arteriosus and fetal and renal dysfunction leading to oligohydramnios and, in some cases, neonatal renal impairment.

C

Category C — Use Cautiously

Animal studies show adverse effects; weigh benefits vs. risks.

Brands Available in India

Naproxen Sodium(275 Mg) is sold under these common brand names. All contain the same active ingredient, so safety during pregnancy is identical. Tap any brand for detailed info.

AI-Verified · Based on FDA classifications + peer-reviewed sources

Not medical advice

Every pregnancy is different. Always consult your obstetrician before taking any medicine. Drug safety classifications can change — verify current guidelines with your doctor. For emergencies, call 112.

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