Metoprolol(25 Mg)+ Amlodipine(5 Mg) in pregnancy: classified as Category C. Metoprolol(25 Mg)+ Amlodipine(5 Mg) pregnancy safety: Category C — Use with caution. Risk Summary Untreated hypertension and heart failure during pregnancy can lead to adverse outcomes

Pregnancy SafetyUse With CautionFDA Cat. CAI-Verified

Is Metoprolol(25 Mg)+ Amlodipine(5 Mg) safe during pregnancy?

Risk Summary Untreated hypertension and heart failure during pregnancy can lead to adverse outcomes for the mother and the fetus (see Clinical Considerations). Available data from published observational studies have not demonstrated a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes with metoprolol use during pregnancy.

SAFECAUTIONAVOID

Overall verdict

Use With Caution

Trimester-by-Trimester Guide

40 weeks · 3 stages · different risks

AVOID
AVOID
AVOID
Week 1
Week 13
Week 27Week 40
Avoid

1st Trimester

Weeks 1–12 · Organs forming

Risk Summary Untreated hypertension and heart failure during pregnancy can lead to adverse outcomes for the mother and the fetus (see Clinical Considerations). Available data from published observational studies have not demonstrated a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes with metoprolol use during pregnancy.

Avoid

2nd Trimester

Weeks 13–26 · Baby growing

Risk Summary Untreated hypertension and heart failure during pregnancy can lead to adverse outcomes for the mother and the fetus (see Clinical Considerations). Available data from published observational studies have not demonstrated a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes with metoprolol use during pregnancy.

Avoid

3rd Trimester

Weeks 27–40 · Final development

Risk Summary Untreated hypertension and heart failure during pregnancy can lead to adverse outcomes for the mother and the fetus (see Clinical Considerations). Available data from published observational studies have not demonstrated a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes with metoprolol use during pregnancy.

C

Category C — Use Cautiously

Animal studies show adverse effects; weigh benefits vs. risks.

Brands Available in India

Metoprolol(25 Mg)+ Amlodipine(5 Mg) is sold under these common brand names. All contain the same active ingredient, so safety during pregnancy is identical. Tap any brand for detailed info.

AI-Verified · Based on FDA classifications + peer-reviewed sources

Not medical advice

Every pregnancy is different. Always consult your obstetrician before taking any medicine. Drug safety classifications can change — verify current guidelines with your doctor. For emergencies, call 112.

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