Is Caffeine(25.0 Mg)+ Phenylephrine(5.0 Mg)+ Chlorpheniramine(2.0 Mg)+ Paracetamol(325.0 Mg) safe during pregnancy?
Risk Summary Use of opioid analgesics for an extended period of time during pregnancy may cause neonatal opioid withdrawal syndrome [see Warnings and Precautions ] . Use of NSAIDs, including aspirin, can cause premature closure of the fetal ductus arteriosus and fetal renal dysfunction leading to oligohydramnios and, in some cases, neonatal renal impairment.
Overall verdict
Use With Caution
Trimester-by-Trimester Guide
40 weeks · 3 stages · different risks
1st Trimester
Weeks 1–12 · Organs forming
Risk Summary Use of opioid analgesics for an extended period of time during pregnancy may cause neonatal opioid withdrawal syndrome [see Warnings and Precautions ] . Use of NSAIDs, including aspirin, can cause premature closure of the fetal ductus arteriosus and fetal renal dysfunction leading to oligohydramnios and, in some cases, neonatal renal impairment.
2nd Trimester
Weeks 13–26 · Baby growing
Risk Summary Use of opioid analgesics for an extended period of time during pregnancy may cause neonatal opioid withdrawal syndrome [see Warnings and Precautions ] . Use of NSAIDs, including aspirin, can cause premature closure of the fetal ductus arteriosus and fetal renal dysfunction leading to oligohydramnios and, in some cases, neonatal renal impairment.
3rd Trimester
Weeks 27–40 · Final development
Risk Summary Use of opioid analgesics for an extended period of time during pregnancy may cause neonatal opioid withdrawal syndrome [see Warnings and Precautions ] . Use of NSAIDs, including aspirin, can cause premature closure of the fetal ductus arteriosus and fetal renal dysfunction leading to oligohydramnios and, in some cases, neonatal renal impairment.
Category C — Use Cautiously
Animal studies show adverse effects; weigh benefits vs. risks.
Brands Available in India
Caffeine(25.0 Mg)+ Phenylephrine(5.0 Mg)+ Chlorpheniramine(2.0 Mg)+ Paracetamol(325.0 Mg) is sold under these common brand names. All contain the same active ingredient, so safety during pregnancy is identical. Tap any brand for detailed info.
Not medical advice
Every pregnancy is different. Always consult your obstetrician before taking any medicine. Drug safety classifications can change — verify current guidelines with your doctor. For emergencies, call 112.
Frequently Asked Questions
Pregnancy specific sawaal? AI se directly pooch lo.
Caffeine(25.0 Mg)+ Phenylephrine(5.0 Mg)+ Chlorpheniramine(2.0 Mg)+ Paracetamol(325.0 Mg) dose, safer alternatives, trimester-specific guidance — apni language mein.