Thyroxine (also known as 3,5,3',5'-Tetraiodothyronine, T4 Thyroid Hormone): The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by p
The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism.
MeSH classification
D06.472.931.812
D12.125.072.050.767
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The major hormone derived from the thyroid gland. Thyroxine is synthesized via the iodination of tyrosines (MONOIODOTYROSINE) and the coupling of iodotyrosines (DIIODOTYROSINE) in the THYROGLOBULIN. Thyroxine is released from thyroglobulin by proteolysis and secreted into the blood. Thyroxine is peripherally deiodinated to form TRIIODOTHYRONINE which exerts a broad spectrum of stimulatory effects on cell metabolism. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Thyroxine known by any other names?
Yes. Thyroxine is also referred to as 3,5,3',5'-Tetraiodothyronine, T4 Thyroid Hormone, Thyroid Hormone, T4, Thyroxin in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Thyroxine sit in the medical classification?
Thyroxine falls under the broader medical category "Chemicals and Drugs" in the MeSH hierarchy (tree numbers: D06.472.931.812, D12.125.072.050.767). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
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