Myasthenia Gravis, Neonatal (also known as Neonatal Myasthenia Gravis, Antenatal Myasthenia Gravis): A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually present at birth or develop in the first 3 days of life and consist of h
A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually present at birth or develop in the first 3 days of life and consist of hypotonia and impaired respiratory, suck, and swallowing abilities. This condition is associated with the passive transfer of acetylcholine receptor antibodies through the placenta. In the majority of infants the myasthenic weakness resolves (i.e., transient neonatal myasthenia gravis) although this disorder may rarely continue beyond the neonatal period (i.e., persistent neonatal myasthenia gravis). (From Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology 1997 Jan;48(1):50-4)
MeSH classification
C10.114.656.650
C10.668.758.725.650
C20.111.258.500.650
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Common questions about Myasthenia Gravis, Neonatal
What does Myasthenia Gravis, Neonatal mean in medicine?
A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually present at birth or develop in the first 3 days of life and consist of hypotonia and impaired respiratory, suck, and swallowing abilities. This condition is associated with the passive transfer of acetylcholine receptor antibodies through the placenta. In the majority of infants the myasthenic weakness resolves (i.e., transient neonatal myasthenia gravis) although this disorder may rarely continue beyond the neonatal period (i.e., persistent neonatal myasthenia gravis). (From Menkes, Textbook of Child Neurology, 5th ed, p823; Neurology 1997 Jan;48(1):50-4) This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Myasthenia Gravis, Neonatal known by any other names?
Yes. Myasthenia Gravis, Neonatal is also referred to as Neonatal Myasthenia Gravis, Antenatal Myasthenia Gravis, Myasthenia Gravis, Antenatal, Myasthenia Gravis, Neonatal, Persistent in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Myasthenia Gravis, Neonatal sit in the medical classification?
Myasthenia Gravis, Neonatal falls under the broader medical category "Diseases" in the MeSH hierarchy (tree numbers: C10.114.656.650, C10.668.758.725.650, C20.111.258.500.650). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
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