HIV Envelope Protein gp41 (also known as HIV Transmembrane Protein gp41, Envelope Protein gp41, HIV): Transmembrane envelope protein of the HUMAN IMMUNODEFICIENCY VIRUS which is encoded by the HIV env gene. It has a molecular weight of 41,000 and is glycosylated. The N-terminal part of gp41 is thought to be involved in

NIH MeSH · D015700Chemicals and Drugs

HIV Envelope Protein gp41

Also known asHIV Transmembrane Protein gp41 · Envelope Protein gp41, HIV · env Protein gp41, HIV · gp41(HIV) · gp41 Envelope Protein, HIV · HTLV-III gp41

Definition

Transmembrane envelope protein of the HUMAN IMMUNODEFICIENCY VIRUS which is encoded by the HIV env gene. It has a molecular weight of 41,000 and is glycosylated. The N-terminal part of gp41 is thought to be involved in CELL FUSION with the CD4 ANTIGENS of T4 LYMPHOCYTES, leading to syncytial formation. Gp41 is one of the most common HIV antigens detected by IMMUNOBLOTTING.

MeSH classification

  • D12.776.543.512.500.330
  • D12.776.964.350.520.330
  • D12.776.964.775.325.164.200
  • D12.776.964.775.562.500.200
  • D12.776.964.970.880.325.164.200
  • D12.776.964.970.880.910.330
  • D23.050.327.520.330

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Common questions about HIV Envelope Protein gp41

What does HIV Envelope Protein gp41 mean in medicine?
Transmembrane envelope protein of the HUMAN IMMUNODEFICIENCY VIRUS which is encoded by the HIV env gene. It has a molecular weight of 41,000 and is glycosylated. The N-terminal part of gp41 is thought to be involved in CELL FUSION with the CD4 ANTIGENS of T4 LYMPHOCYTES, leading to syncytial formation. Gp41 is one of the most common HIV antigens detected by IMMUNOBLOTTING. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is HIV Envelope Protein gp41 known by any other names?
Yes. HIV Envelope Protein gp41 is also referred to as HIV Transmembrane Protein gp41, Envelope Protein gp41, HIV, env Protein gp41, HIV, gp41(HIV) in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does HIV Envelope Protein gp41 sit in the medical classification?
HIV Envelope Protein gp41 falls under the broader medical category "Chemicals and Drugs" in the MeSH hierarchy (tree numbers: D12.776.543.512.500.330, D12.776.964.350.520.330, D12.776.964.775.325.164.200). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of HIV Envelope Protein gp41?
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Source: NIH MeSH 2026 (D015700) — National Library of Medicine, public domain. View official MeSH record ↗