Chemokine CXCL16 (also known as CXCL16, Chemokine, CXC Chemokine Ligand 16): A CXCR6 receptor-binding chemokine that functions as a scavenger receptor for oxidized low density lipoprotein (OxLDL) when expressed by MACROPHAGES. Its secreted, or cytokine form induces a strong chemotactic response for MONOCYTES when it is

NIH MeSH · D000075743Chemicals and Drugs

Chemokine CXCL16

Also known asCXCL16, Chemokine · CXC Chemokine Ligand 16 · SR-PSOX

Definition

A CXCR6 receptor-binding chemokine that functions as a scavenger receptor for oxidized low density lipoprotein (OxLDL) when expressed by MACROPHAGES. Its secreted, or cytokine form induces a strong chemotactic response for MONOCYTES when it is expressed by DENDRITIC CELLS.

MeSH classification

  • D12.644.276.374.200.120.075
  • D12.776.467.374.200.120.075
  • D12.776.503.280.718.500
  • D12.776.543.750.705.940.734.500
  • D12.776.543.750.710.450.625.500.500
  • D12.776.543.750.710.450.750.734.500
  • D23.125.300.120.075
  • D23.469.200.120.075
  • D23.529.374.200.120.075

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Common questions about Chemokine CXCL16

What does Chemokine CXCL16 mean in medicine?
A CXCR6 receptor-binding chemokine that functions as a scavenger receptor for oxidized low density lipoprotein (OxLDL) when expressed by MACROPHAGES. Its secreted, or cytokine form induces a strong chemotactic response for MONOCYTES when it is expressed by DENDRITIC CELLS. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Chemokine CXCL16 known by any other names?
Yes. Chemokine CXCL16 is also referred to as CXCL16, Chemokine, CXC Chemokine Ligand 16, SR-PSOX in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Chemokine CXCL16 sit in the medical classification?
Chemokine CXCL16 falls under the broader medical category "Chemicals and Drugs" in the MeSH hierarchy (tree numbers: D12.644.276.374.200.120.075, D12.776.467.374.200.120.075, D12.776.503.280.718.500). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of Chemokine CXCL16?
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Source: NIH MeSH 2026 (D000075743) — National Library of Medicine, public domain. View official MeSH record ↗