Biomolecular Condensates (also known as Biomolecular Condensate, Condensate, Biomolecular): Membraneless intracellular compartments formed through liquid-liquid phase separation from the surrounding CYTOPLASM or nucleoplasm or by the concentration of proteins and nucleic acids into droplets as they aggregate on static

NIH MeSH · D000091582Anatomy

Biomolecular Condensates

Also known asBiomolecular Condensate · Condensate, Biomolecular · Condensates, Biomolecular · Membraneless Organelles · Membraneless Organelle · Organelle, Membraneless · Organelles, Membraneless

Definition

Membraneless intracellular compartments formed through liquid-liquid phase separation from the surrounding CYTOPLASM or nucleoplasm or by the concentration of proteins and nucleic acids into droplets as they aggregate on static cellular structures such as CELL MEMBRANES. Examples include CELL NUCLEOLI; STRESS GRANULES; PARASPECKLES; HISTONE LOCUS BODIES; and POSTSYNAPTIC DENSITIES.

MeSH classification

  • A11.284.037

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Related concepts

Common questions about Biomolecular Condensates

What does Biomolecular Condensates mean in medicine?
Membraneless intracellular compartments formed through liquid-liquid phase separation from the surrounding CYTOPLASM or nucleoplasm or by the concentration of proteins and nucleic acids into droplets as they aggregate on static cellular structures such as CELL MEMBRANES. Examples include CELL NUCLEOLI; STRESS GRANULES; PARASPECKLES; HISTONE LOCUS BODIES; and POSTSYNAPTIC DENSITIES. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Biomolecular Condensates known by any other names?
Yes. Biomolecular Condensates is also referred to as Biomolecular Condensate, Condensate, Biomolecular, Condensates, Biomolecular, Membraneless Organelles in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Biomolecular Condensates sit in the medical classification?
Biomolecular Condensates falls under the broader medical category "Anatomy" in the MeSH hierarchy (tree numbers: A11.284.037). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of Biomolecular Condensates?
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Source: NIH MeSH 2026 (D000091582) — National Library of Medicine, public domain. View official MeSH record ↗