Base Pair Mismatch (also known as Mismatch, Base Pair, Base Pair Mismatches): The presence of an non-complementary base in double-stranded DNA (DNA mismatch) caused by spontaneous deamination of cytosine or adenine, mismatching during homologous recombination, small insertions or deletions, or errors in DNA replication

NIH MeSH · D020137Phenomena and Processes

Base Pair Mismatch

Also known asMismatch, Base Pair · Base Pair Mismatches · Mismatches, Base Pair

Definition

The presence of an non-complementary base in double-stranded DNA (DNA mismatch) caused by spontaneous deamination of cytosine or adenine, mismatching during homologous recombination, small insertions or deletions, or errors in DNA replication. Multiple, sequential base pair mismatches lead to formation of heteroduplex DNA; (NUCLEIC ACID HETERODUPLEXES).

MeSH classification

  • G05.200.052
  • G05.365.590.060

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Common questions about Base Pair Mismatch

What does Base Pair Mismatch mean in medicine?
The presence of an non-complementary base in double-stranded DNA (DNA mismatch) caused by spontaneous deamination of cytosine or adenine, mismatching during homologous recombination, small insertions or deletions, or errors in DNA replication. Multiple, sequential base pair mismatches lead to formation of heteroduplex DNA; (NUCLEIC ACID HETERODUPLEXES). This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Base Pair Mismatch known by any other names?
Yes. Base Pair Mismatch is also referred to as Mismatch, Base Pair, Base Pair Mismatches, Mismatches, Base Pair in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Base Pair Mismatch sit in the medical classification?
Base Pair Mismatch falls under the broader medical category "Phenomena and Processes" in the MeSH hierarchy (tree numbers: G05.200.052, G05.365.590.060). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of Base Pair Mismatch?
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Source: NIH MeSH 2026 (D020137) — National Library of Medicine, public domain. View official MeSH record ↗