Arthus Reaction (also known as Reaction, Arthus, Arthus Phenomenon): A dermal inflammatory reaction produced under conditions of antibody excess, when a second injection of antigen produces intravascular antigen-antibody complexes which bind complement, causing cell clumping, endothelial damage, and vascular necrosis.

NIH MeSH · D001183Diseases

Arthus Reaction

Also known asReaction, Arthus · Arthus Phenomenon · Phenomenon, Arthus

Definition

A dermal inflammatory reaction produced under conditions of antibody excess, when a second injection of antigen produces intravascular antigen-antibody complexes which bind complement, causing cell clumping, endothelial damage, and vascular necrosis.

MeSH classification

  • C20.543.520.175

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Common questions about Arthus Reaction

What does Arthus Reaction mean in medicine?
A dermal inflammatory reaction produced under conditions of antibody excess, when a second injection of antigen produces intravascular antigen-antibody complexes which bind complement, causing cell clumping, endothelial damage, and vascular necrosis. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Arthus Reaction known by any other names?
Yes. Arthus Reaction is also referred to as Reaction, Arthus, Arthus Phenomenon, Phenomenon, Arthus in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Arthus Reaction sit in the medical classification?
Arthus Reaction falls under the broader medical category "Diseases" in the MeSH hierarchy (tree numbers: C20.543.520.175). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of Arthus Reaction?
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Source: NIH MeSH 2026 (D001183) — National Library of Medicine, public domain. View official MeSH record ↗