Antibody-Dependent Enhancement

Enhancement of viral infectivity caused by non-neutralizing antibodies. There are at least two mechanisms known to account for this: mediation by Fc receptors (RECEPTORS, FC) or by complement receptors (RECEPTORS, COMPLEMENT). Either the virus is complexed with antiviral IMMUNOGLOBULIN G and binds to Fc receptors, or virus is coated with antiviral IMMUNOGLOBULIN M and binds to complement receptors. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.

Yes. Antibody-Dependent Enhancement is also referred to as Antibody Dependent Enhancement, Antibody-Dependent Enhancements, Enhancement, Antibody-Dependent in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.

Antibody-Dependent Enhancement falls under the broader medical category "Phenomena and Processes" in the MeSH hierarchy (tree numbers: G06.920.095, G12.113). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.

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