alpha-Thalassemia (also known as alpha-Thalassemias, Thalassemia-alpha): A disorder characterized by reduced synthesis of the alpha chains of hemoglobin. The severity of this condition can vary from mild anemia to death, depending on the number of genes deleted.

NIH MeSH · D017085Diseases

alpha-Thalassemia

Also known asalpha-Thalassemias · Thalassemia-alpha · Thalassemia alpha · Hemoglobin H Disease · Disease, Hemoglobin H · Alpha Thalassemia · Thalassemia, Alpha · A-Thalassemia

Definition

A disorder characterized by reduced synthesis of the alpha chains of hemoglobin. The severity of this condition can vary from mild anemia to death, depending on the number of genes deleted.

MeSH classification

  • C15.378.050.141.150.875.100
  • C15.378.420.826.100
  • C16.320.070.875.100
  • C16.320.365.826.100

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Common questions about alpha-Thalassemia

What does alpha-Thalassemia mean in medicine?
A disorder characterized by reduced synthesis of the alpha chains of hemoglobin. The severity of this condition can vary from mild anemia to death, depending on the number of genes deleted. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is alpha-Thalassemia known by any other names?
Yes. alpha-Thalassemia is also referred to as alpha-Thalassemias, Thalassemia-alpha, Thalassemia alpha, Hemoglobin H Disease in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does alpha-Thalassemia sit in the medical classification?
alpha-Thalassemia falls under the broader medical category "Diseases" in the MeSH hierarchy (tree numbers: C15.378.050.141.150.875.100, C15.378.420.826.100, C16.320.070.875.100). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of alpha-Thalassemia?
For a plain-language explanation of alpha-Thalassemia - including symptoms, treatments and what it means for an Indian patient - ask GoDavaii's Health AI. It works in 22+ Indian languages, is free and needs no signup. Tap "Ask GoDavaii AI about alpha-Thalassemia" above.

Source: NIH MeSH 2026 (D017085) — National Library of Medicine, public domain. View official MeSH record ↗