Abciximab (also known as Chimeric 7E3 Fab, Fab, Chimeric 7E3): A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory

NIH MeSH · D000077284Chemicals and Drugs

Abciximab

Also known asChimeric 7E3 Fab · Fab, Chimeric 7E3 · c7E3 Fab · CentoRx · ReoPro · Clotinab

Definition

A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in patients undergoing percutaneous coronary procedures such as ANGIOPLASTY; ATHERECTOMY; or stenting.

MeSH classification

  • D12.644.541.500.650.125
  • D12.776.124.486.485.114.224.060.125
  • D12.776.124.486.485.680.650.125
  • D12.776.124.790.651.114.224.060.125
  • D12.776.124.790.651.680.650.125
  • D12.776.377.715.548.114.224.200.125
  • D12.776.377.715.548.680.650.125

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Common questions about Abciximab

What does Abciximab mean in medicine?
A Fab fragment of the chimeric monoclonal antibody 7E3 that binds to the glycoprotein IIb-IIIa receptor of human platelets, and blocks PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX, potently inhibiting PLATELET AGGREGATION. It is used in treatment of refractory unstable angina, and for prevention of ischemic complications in patients undergoing percutaneous coronary procedures such as ANGIOPLASTY; ATHERECTOMY; or stenting. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is Abciximab known by any other names?
Yes. Abciximab is also referred to as Chimeric 7E3 Fab, Fab, Chimeric 7E3, c7E3 Fab, CentoRx in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does Abciximab sit in the medical classification?
Abciximab falls under the broader medical category "Chemicals and Drugs" in the MeSH hierarchy (tree numbers: D12.644.541.500.650.125, D12.776.124.486.485.114.224.060.125, D12.776.124.486.485.680.650.125). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of Abciximab?
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Source: NIH MeSH 2026 (D000077284) — National Library of Medicine, public domain. View official MeSH record ↗