3-Iodobenzylguanidine (also known as 3 Iodobenzylguanidine, Iobenguane): A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blo

NIH MeSH · D019797Chemicals and Drugs

3-Iodobenzylguanidine

Also known as3 Iodobenzylguanidine · Iobenguane · m-Iodobenzylguanidine · m Iodobenzylguanidine · meta-Iodobenzylguanidine · meta Iodobenzylguanidine · MIBG · (3-Iodo-(131I)benzyl)guanidine · Iobenguane (131I) · 3-Iodobenzylguanidine, 125I Labeled · 125I Labeled 3-Iodobenzylguanidine · 3 Iodobenzylguanidine, 125I Labeled

Definition

A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase.

MeSH classification

  • D02.078.370.510
  • D02.455.426.559.389.454.300
  • D02.455.526.581.496.300

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Common questions about 3-Iodobenzylguanidine

What does 3-Iodobenzylguanidine mean in medicine?
A guanidine analog with specific affinity for tissues of the sympathetic nervous system and related tumors. The radiolabeled forms are used as antineoplastic agents and radioactive imaging agents. (Merck Index, 12th ed) MIBG serves as a neuron-blocking agent which has a strong affinity for, and retention in, the adrenal medulla and also inhibits ADP-ribosyltransferase. This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is 3-Iodobenzylguanidine known by any other names?
Yes. 3-Iodobenzylguanidine is also referred to as 3 Iodobenzylguanidine, Iobenguane, m-Iodobenzylguanidine, m Iodobenzylguanidine in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does 3-Iodobenzylguanidine sit in the medical classification?
3-Iodobenzylguanidine falls under the broader medical category "Chemicals and Drugs" in the MeSH hierarchy (tree numbers: D02.078.370.510, D02.455.426.559.389.454.300, D02.455.526.581.496.300). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of 3-Iodobenzylguanidine?
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Source: NIH MeSH 2026 (D019797) — National Library of Medicine, public domain. View official MeSH record ↗