2-Aminoadipic Acid (also known as Acid, 2-Aminoadipic, 2 Aminoadipic Acid): A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).

NIH MeSH · D015074Chemicals and Drugs

2-Aminoadipic Acid

Also known asAcid, 2-Aminoadipic · 2 Aminoadipic Acid · Acid, 2 Aminoadipic · Aminoadipic Acid, 2 · 2-Aminohexanedioic Acid · 2 Aminohexanedioic Acid · Acid, 2-Aminohexanedioic · alpha-Aminoadipic Acid · Acid, alpha-Aminoadipic · alpha Aminoadipic Acid

Definition

A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA).

MeSH classification

  • D02.241.081.337.052.075
  • D12.125.119.075

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Common questions about 2-Aminoadipic Acid

What does 2-Aminoadipic Acid mean in medicine?
A metabolite in the principal biochemical pathway of lysine. It antagonizes neuroexcitatory activity modulated by the glutamate receptor, N-METHYL-D-ASPARTATE; (NMDA). This definition is taken from the National Library of Medicine's MeSH (Medical Subject Headings) 2026 release, which is the standard vocabulary used to index PubMed and most medical literature.
Is 2-Aminoadipic Acid known by any other names?
Yes. 2-Aminoadipic Acid is also referred to as Acid, 2-Aminoadipic, 2 Aminoadipic Acid, Acid, 2 Aminoadipic, Aminoadipic Acid, 2 in different clinical, research and patient-facing contexts. The MeSH descriptor groups all of these synonyms under a single canonical concept so research and records stay consistent.
Where does 2-Aminoadipic Acid sit in the medical classification?
2-Aminoadipic Acid falls under the broader medical category "Chemicals and Drugs" in the MeSH hierarchy (tree numbers: D02.241.081.337.052.075, D12.125.119.075). Browsing the related concepts on this page takes you to neighbouring topics in the same branch of medicine.
Where can I get a plain-language explanation of 2-Aminoadipic Acid?
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Source: NIH MeSH 2026 (D015074) — National Library of Medicine, public domain. View official MeSH record ↗