Cevimeline - Warnings and Precautions
The following warnings and precautions are taken directly from the US FDA-approved drug label for Cevimeline. This is the same information dispensing pharmacists read.
WARNINGS Cardiovascular Disease: Cevimeline can potentially alter cardiac conduction and/or heart rate.
Patients with significant cardiovascular disease may potentially be unable to compensate for transient changes in hemodynamics or rhythm induced by Cevimeline Hydrochloride Capsules.
Cevimeline Hydrochloride Capsules should be used with caution and under close medical supervision in patients with a history of cardiovascular disease evidenced by angina pectoris or myocardial infarction.
Pulmonary Disease: Cevimeline can potentially increase airway resistance, bronchial smooth muscle tone, and bronchial secretions.
Cevimeline should be administered with caution and with close medical supervision to patients with controlled asthma, chronic bronchitis, or chronic obstructive pulmonary disease.
Ocular: Ophthalmic formulations of muscarinic agonists have been reported to cause visual blurring which may result in decreased visual acuity, especially at night and in patients with central lens changes, and to cause impairment of depth perception.
Caution should be advised while driving at night or performing hazardous activities in reduced lighting.
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