Gefitinib Overdose

10 OVERDOSAGE Twenty three patients were treated weekly with doses from 1,500 mg to 3,500 mg, and gefitinib tablets exposure did not increase with increasing dose.

Adverse events were mostly mild to moderate in severity, and were consistent with the known safety profile of gefitinib tablets.

In the event of suspected overdose, interrupt gefitinib tablets, institute supportive care, and observe until clinical stabilization.

There are no specific measures/treatments that should be taken following gefitinib tablets overdosing.