Paroxetine - Contraindications
These conditions, allergies, and situations mean Paroxetine should NOT be used. From the US FDA-approved drug label Section 4.
CONTRAINDICATIONS The use of MAOIs intended to treat psychiatric disorders with paroxetine tablets or within 14 days of stopping treatment with paroxetine tablets is contraindicated because of an increased risk of serotonin syndrome.
The use of paroxetine within 14 days of stopping an MAOI intended to treat psychiatric disorders is also contraindicated (see WARNINGS and DOSAGE AND ADMINISTRATION ).
Starting paroxetine tablets in a patient who is being treated with MAOIs such as linezolid or intravenous methylene blue is also contraindicated because of an increased risk of serotonin syndrome (see WARNINGS and DOSAGE AND ADMINISTRATION ).
Concomitant use with thioridazine is contraindicated (see WARNINGS and PRECAUTIONS ).
Concomitant use in patients taking pimozide is contraindicated (see PRECAUTIONS ).
Paroxetine tablets are contraindicated in patients with a hypersensitivity to paroxetine or any of the inactive ingredients in paroxetine tablets.