FDA Section 4 \u2022 who must NOT take this
Papaverine - Contraindications
These conditions, allergies, and situations mean Papaverine should NOT be used. From the US FDA-approved drug label Section 4.
CONTRAINDICATIONS Intravenous injection of papaverine is contraindicated in the presence of complete atrioventricular heart block.
When conduction is depressed, the drug may produce transient ectopic rhythms of ventricular origin, either premature beats or paroxysmal tachycardia.
Papaverine Hydrochloride is not indicated for the treatment of impotence by intracorporeal injection.
The intracorporeal injection of papaverine hydrochloride has been reported to have resulted in persistent priapism requiring medical and surgical intervention.